Exploring Phylogenetic Relationships between Hundreds of Plant Fatty Acids Synthesized by Thousands of Plants. more details ...
Abstract The acyl composition of phosphatidylinositol (PI) is remarkably resistant to dietary fatty acid modification. To investigate the basis of this selectivity, we have probed fatty acids lacking the usual methylene interrupted double bonds. When mice were fed Δ-5,11,14 20:3 as 3% of total lipid, this fatty acid, lacking the Δ-8 double bond essential for eicosanoid synthesis, replaced a significant quantity of 20:4(n - 6) in PI, but not PC and PE. By altering the acyl composition of PI, novel second messengers may be formed. This fatty acid structure thus provides a unique nutritional tool for investigating the basis of PI acyl specificity, and for determining the metabolic consequences of acyl alteration, in vivo. © 1991.

Authors: Berger, A.; Bruce German, J.

Journal: Biochimica et Biophysica Acta (BBA)/Lipids and Lipid Metabolism

Year: 1991

Volume: 1085

Page: 371-376

UID: WOS:A1991GL97800011

URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-0025936413&partnerID=40&md5=4101139a139002204c1ea2a979eca67a

DOI: 10.1016/0005-2760(91)90142-5

Plants View All 2 Datasets
Genus Species Data Points
Aquilegia vulgaris 13
Platycladus orientalis 13
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