Multivariate optimization of a gas-liquid chromatographic analysis of fatty acid methyl esters of blackcurrant seed oil

Abstract

A method was investigated and optimized for the analysis of fatty acid methyl esters using blackcurrant (Ribes nigrum) seed oil as a model. This was done with a total of eight runs, utilizing experimental design to explore the experimental domain, a multivariate ranking function to rank the chromatograms and response-surface methods to locate an optimum.